“Oxygenated three-dimensional scaffolds for pancreatic endocrine differentiation from iPSCs.” Hui Huang, Soujanya S Karanth, Ya Guan, Sebastian Freeman, Ryan Soron, David S Godovich, Jianjun Guan, Kaiming Ye, Sha Jin. Submitted.

“Co-delivery of bioengineered exosomes and oxygen for treating critical limb ischemia in diabetic mice.” Zhong T, Gao N, Guan Y, Liu Z, Guan J. Under Revision.

“DNA methylation mediated Rbpjk suppression protects against fracture nonunion caused by systemic inflammation.” Xiao D, Wang C, Fang L, Liu Z, He Y, Ying J, Qin H, Lu A, Abu-Amer Y, Guan J, Shen J. Under Revision.

“Thermosensitive and Antioxidant Wound Dressings Capable of Adaptively Regulating TGFβ Pathways Promote Diabetic Wound Healing.” Niu H, Guan Y, Zhong T, Ma L, Zayed M, Guan J. npj Regenerative Medicine. 2023 Jul 8; 8(1):32. doi: 10.1038/s41536-023-00313-3. https://pubmed.ncbi.nlm.nih.gov/37422462/

“Rescuing Cardiac Cells and Improving Cardiac Function by Targeted Delivery of Oxygen-Releasing Nanoparticles after or Even before Acute Myocardial Infarction.” Guan Y, Niu H, Wen J, Dang Y, Zayed M, Guan J. ACS Nano. 2022 Nov 11. doi: 10.1021/acsnano.2c10043.  https://pubmed.ncbi.nlm.nih.gov/36367231/

“Sustained delivery of rhMG53 promotes diabetic wound healing and hair follicle development.” Niu H, Li H, Guan Y, Zhou X, Li Z, Zhao SL, Chen P, Tan T, Zhu H, Bergdall V, Xu X, Ma J, Guan J. Bioact Mater. 2022 Mar 16;18:104-115. https://pubmed.ncbi.nlm.nih.gov/35387169/

“Delivery of VEGF and delta-like 4 to synergistically regenerate capillaries and arterioles in ischemic limbs.” Niu H, Gao N, Dang Y, Guan Y, Guan J. Acta Biomater. 2022 Apr 15;143:295-309. https://pubmed.ncbi.nlm.nih.gov/35301145/

“Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation.” Guan Y, Niu H, Liu Z, Dang Y, Shen J, Zayed M, Ma L, Guan J. Sci Adv. 2021 Aug 27;7(35):eabj0153. https://pubmed.ncbi.nlm.nih.gov/34452918/

“Oxygen-release microspheres capable of releasing oxygen in response to environmental oxygen level to improve stem cell survival and tissue regeneration in ischemic hindlimbs.” Guan Y, Gao N, Niu H, Dang Y, Guan J. J Control Release. 2021 Mar 10;331:376-389. https://pubmed.ncbi.nlm.nih.gov/33508351/

“Targeted Delivery of a Matrix Metalloproteinases-2 Specific Inhibitor Using Multifunctional Nanogels to Attenuate Ischemic Skeletal Muscle Degeneration and Promote Revascularization.” Dang Y, Gao N, Niu H, Guan Y, Fan Z, Guan J. ACS Appl Mater Interfaces. 2021 Feb 10;13(5):5907-5918. https://pubmed.ncbi.nlm.nih.gov/33506676/

“Targeting angiogenesis for fracture nonunion treatment in inflammatory disease.” Wang C, Ying J, Nie X, Zhou T, Xiao D, Swarnkar G, Abu-Amer Y, Guan J, Shen J. Bone Res. 2021, 9(1):29.https://pubmed.ncbi.nlm.nih.gov/34099632/

“Photoluminescent oxygen-release microspheres to image the oxygen release process in vivo.” Guan Y, Niu H, Dang Y, Gao N, Guan J. Acta Biomater. 2020 Oct 1;115:333-342. https://pubmed.ncbi.nlm.nih.gov/32853800/

“High oxygen preservation hydrogels to augment cell survival under hypoxic condition.” Niu H, Li C, Guan Y, Dang Y, Li X, Fan Z, Shen J, Ma L, Guan J. Acta Biomater. 2020 Mar 15;105:56-67. https://pubmed.ncbi.nlm.nih.gov/31954189/

“Nanoparticle-based drug delivery systems for cancer therapy.” Dang Y, Guan J. Smart Mater Med. 2020;1:10-19. https://pubmed.ncbi.nlm.nih.gov/34553138/

“Dnmt3b Ablation Impairs Fracture Repair Through Upregulation of Notch Pathway.” Jun Ying, Taotao Xu, Cuicui Wang, Hongting Jin, Peijian Tong, Jianjun Guan, Yousef Abu-Amer, Regis O’Keefe, Jie Shen. JCI Insight. 2020, 5(3):e131816. https://pubmed.ncbi.nlm.nih.gov/32051335/

“Spatiotemporal delivery of basic fibroblast growth factor to directly and simultaneously attenuate cardiac fibrosis and promote cardiac tissue vascularization following myocardial infarction.” Fan Z, Xu Z, Niu H, Sui Y, Li H, Ma J, Guan J. J Control Release. 2019 Oct;311-312:233-244. https://pubmed.ncbi.nlm.nih.gov/31521744/

“Injectable Oxygen Sensitive Chitosan Complex with High Oxygen Sensitivity and Stability to Oxidoreductants.” Li C, Huang Z, Gao N, Sui Y, Niu H, Guan J. ACS Biomater Sci Eng. 2019 May 13;5(5):2173-2179. https://pubmed.ncbi.nlm.nih.gov/32856002/

“Injectable, thermosensitive, fast gelation, bioeliminable, and oxygen sensitive hydrogels.” Li C, Huang Z, Gao N, Zheng J, Guan J. Mater Sci Eng C Mater Biol Appl. 2019 Jun;99:1191-1198. https://pubmed.ncbi.nlm.nih.gov/30889653/

“Thermosensitive, fast gelling, photoluminescent, highly flexible, and degradable hydrogels for stem cell delivery.” Niu H, Li X, Li H, Fan Z, Ma J, Guan J. Acta Biomater. 2019 Jan 1;83:96-108. https://pubmed.ncbi.nlm.nih.gov/30541703/

“Biomimetic polyurethane/TiO2 nanocomposite scaffolds capable of promoting biomineralization and mesenchymal stem cell proliferation.” Zhu Q, Li X, Fan Z, Xu Y, Niu H, Li C, Dang Y, Huang Z, Wang Y, Guan J. Mater Sci Eng C Mater Biol Appl. 2018 Apr 1;85:79-87. https://pubmed.ncbi.nlm.nih.gov/29407160/

“An Injectable Oxygen Release System to Augment Cell Survival and Promote Cardiac Repair Following Myocardial Infarction.” Fan Z, Xu Z, Niu H, Gao N, Guan Y, Li C, Dang Y, Cui X, Liu XL, Duan Y, Li H, Zhou X, Lin PH, Ma J, Guan J. Sci Rep. 2018 Jan 22;8(1):1371. https://pubmed.ncbi.nlm.nih.gov/29358595/

“Sustained Release of a Peptide-Based Matrix Metalloproteinase-2 Inhibitor to Attenuate Adverse Cardiac Remodeling and Improve Cardiac Function Following Myocardial Infarction.” Fan Z, Fu M, Xu Z, Zhang B, Li Z, Li H, Zhou X, Liu X, Duan Y, Lin PH, Duann P, Xie X, Ma J, Liu Z, Guan J. Biomacromolecules. 2017 Sep 11;18(9):2820-2829. https://pubmed.ncbi.nlm.nih.gov/28731675/

“Modeling Spatial Distribution of Oxygen in 3D Culture of Islet beta-Cells.” John McReynolds, Xiaofei Li, Jianjun Guan, Sha Jin.  Biotechnology Progress. 2017, 33(1):221-228. https://pubmed.ncbi.nlm.nih.gov/27802569/

“c-kit positive cardiac outgrowth cells demonstrate better ability for cardiac recovery against ischemic myopathy.” Chuan Li, Satoshi Matsushtia, Zhengqing Li, Jianjun Guan, Atsushi Amano. J Stem Cell Res Ther, 2017, 7(10), pii: 402.https://pubmed.ncbi.nlm.nih.gov/29238626/

“Thermosensitive and Highly Flexible Hydrogels Capable of Stimulating Cardiac Differentiation of Cardiosphere-Derived Cells under Static and Dynamic Mechanical Training Conditions.” Li Z, Fan Z, Xu Y, Niu H, Xie X, Liu Z, Guan J. ACS Appl Mater Interfaces. 2016 Jun 29;8(25):15948-57. https://pubmed.ncbi.nlm.nih.gov/27281488/

“Antifibrotic therapies to control cardiac fibrosis.” Fan Z, Guan J. Biomater Res. 2016 May 25;20:13. https://pubmed.ncbi.nlm.nih.gov/27226899/

“pH-Sensitive and Thermosensitive Hydrogels as Stem-Cell Carriers for Cardiac Therapy.” Li Z, Fan Z, Xu Y, Lo W, Wang X, Niu H, Li X, Xie X, Khan M, Guan J. ACS Appl Mater Interfaces. 2016 May 4;8(17):10752-60. https://pubmed.ncbi.nlm.nih.gov/27064934/

“Biomaterial property-controlled stem cell fates for cardiac regeneration.” Xu Y, Guan J. Bioact Mater. 2016 Apr 5;1(1):18-28. https://pubmed.ncbi.nlm.nih.gov/29744392/

“Soft Elasticity-Associated Signaling and Bone Morphogenic Protein 2 Are Key Regulators of Mesenchymal Stem Cell Spheroidal Aggregates.” Cesarz Z, Funnell JL, Guan J, Tamama K. Stem Cells Dev. 2016 Apr 15;25(8):622-35.https://pubmed.ncbi.nlm.nih.gov/26916040/

“A prosurvival and proangiogenic stem cell delivery system to promote ischemic limb regeneration.” Xu Y, Fu M, Li Z, Fan Z, Li X, Liu Y, Anderson PM, Xie X, Liu Z, Guan J. Acta Biomater. 2016 Feb;31:99-113. https://pubmed.ncbi.nlm.nih.gov/26689466/

“Improving Stem and Progenitor Cell Therapeutics.” Kenichi Tamama, Kathryn McFadden, and Jianjun Guan. Stem Cells International. Volume 2016 (2016), Article ID 1409762.https://pubmed.ncbi.nlm.nih.gov/26798351/

“Improving Cell Engraftment in Cardiac Stem Cell Therapy.” Xiaofei Li, Kenichi Tamama, Xiaoyun Xie, and Jianjun Guan. Stem Cells International. Volume 2016 (2016), Article ID 7168797https://pubmed.ncbi.nlm.nih.gov/26783405/

“Establishing Early Functional Perfusion and Structure in Tissue Engineered Cardiac Constructs.” Bo Wang, Sourav S. Patnaik, Bryn Brazile, J. Ryan Butler, Andrew Claude, Ge Zhang, Jianjun Guan, Yi Hong, and Jun Liao. Critical Review in Biomedical Engineering. 2016, 43(5-6):455-71. https://pubmed.ncbi.nlm.nih.gov/27480586/

“Administration of cells with thermosensitive hydrogel enhances the functional recovery in ischemic rat heart.” Satoshi Matsushita,  James S Forrester, Chuan Li, Mitsuru Sato, Zhengqing Li, Xiaolei Guo, Jianjun Guan, Atsushi Amano. J Tissue Eng. 2016;7:2041731416646676.https://pubmed.ncbi.nlm.nih.gov/27213036/